{
 "id": "larsson2006",
 "title": "Larsson & Wolk 2006 (Int J Cancer 119:2657): red meat, highest vs lowest, 15 cohort studies",
 "runs": [
  {
   "name": "CRC HvL – published per-study values (Table I / Fig 1)",
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   "comment": "",
   "rows": [
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     "note": "Table I p2658: 212 cases; total red meat (both reported) | from Fig 1 p. 2660 (render"
    },
    {
     "label": "kato1997",
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     "note": "Table I p2658: 100 cases; excluded from type-of-meat strata (items not specified) | f"
    },
    {
     "label": "chen1998",
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     "note": "Table I p2658: 212 cases; total red meat only | from Fig 1 p. 2660 (rendered): RR (95"
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     "label": "hsing1998",
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     "rr": 1.9,
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     "note": "Table I p2658: 145 cases; total red meat only | from Fig 1 p. 2660 (rendered): RR (95"
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     "label": "singh1998",
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     "note": "Table I p2658: 157 cases; fresh red meat only | from Fig 1 p. 2660 (rendered): RR (95"
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     "label": "pietinen1999",
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     "note": "Table I p2658: 185 cases; total red meat (both reported) | from Fig 1 p. 2660 (render"
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     "label": "jarvinen2001",
     "cohort": "fmches",
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     "note": "Table I p2658: 109 cases; excluded from type-of-meat strata (items not specified) | f"
    },
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     "label": "tiemersma2002",
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     "note": "Table I p2658: 102 cases; fresh red meat only | from Fig 1 p. 2660 (rendered): RR (95"
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     "note": "Table I p2658: 487 cases; total red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
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     "label": "wei2004_nhs",
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     "note": "Table I p2658: 876 cases; fresh red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
    {
     "label": "wei2004_hpfs",
     "cohort": "hpfs",
     "rr": 1.24,
     "lo": 0.78,
     "hi": 1.96,
     "w": 5.228402066512194,
     "note": "Table I p2659: 602 cases; fresh red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
    {
     "label": "english2004",
     "cohort": "mccs",
     "rr": 1.4,
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     "hi": 1.9,
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     "note": "Table I p2659: 451 cases; fresh red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
    {
     "label": "larsson2005",
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     "note": "Table I p2659: 733 cases; total red meat (both reported) | from Fig 1 p. 2660 (render"
    },
    {
     "label": "chao2005",
     "cohort": "cps2",
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     "lo": 0.93,
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     "note": "Table I p2659: 1667 cases; total red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
    {
     "label": "norat2005",
     "cohort": "epic",
     "rr": 1.35,
     "lo": 0.96,
     "hi": 1.88,
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     "note": "Table I p2659: 1329 cases; total red meat (both reported) | from Fig 1 p. 2660 (render"
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   "reproduced": true
  },
  {
   "name": "CRC HvL – corrected: inclusion",
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     "label": "bostick1994",
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     "note": "Table I p2658: 212 cases; total red meat (both reported) | from Fig 1 p. 2660 (render"
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     "label": "kato1997",
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     "w": 3.229464184276307,
     "note": "Table I p2658: 100 cases; excluded from type-of-meat strata (items not specified) | f"
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     "label": "chen1998",
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     "note": "Table I p2658: 212 cases; total red meat only | from Fig 1 p. 2660 (rendered): RR (95"
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     "label": "singh1998",
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     "note": "Table I p2658: 157 cases; fresh red meat only | from Fig 1 p. 2660 (rendered): RR (95"
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    {
     "label": "pietinen1999",
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     "note": "Table I p2658: 185 cases; total red meat (both reported) | from Fig 1 p. 2660 (render"
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     "label": "jarvinen2001",
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     "note": "Table I p2658: 109 cases; excluded from type-of-meat strata (items not specified) | f"
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     "note": "Table I p2658: 102 cases; fresh red meat only | from Fig 1 p. 2660 (rendered): RR (95"
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     "label": "flood2003",
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     "note": "Table I p2658: 487 cases; total red meat only | from Fig 1 p. 2660 (rendered): RR (95"
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    {
     "label": "wei2004_nhs",
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     "note": "Table I p2658: 876 cases; fresh red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
    {
     "label": "wei2004_hpfs",
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     "note": "Table I p2659: 602 cases; fresh red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
    {
     "label": "english2004",
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     "note": "Table I p2659: 451 cases; fresh red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
    {
     "label": "larsson2005",
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     "note": "Table I p2659: 733 cases; total red meat (both reported) | from Fig 1 p. 2660 (render"
    },
    {
     "label": "chao2005",
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     "lo": 0.93,
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     "note": "Table I p2659: 1667 cases; total red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
    {
     "label": "norat2005",
     "cohort": "epic",
     "rr": 1.35,
     "lo": 0.96,
     "hi": 1.88,
     "w": 10.008403188242266,
     "note": "Table I p2659: 1329 cases; total red meat (both reported) | from Fig 1 p. 2660 (render"
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  {
   "name": "CRC HvL – corrected: exposure",
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   "rows": [
    {
     "label": "bostick1994",
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     "w": 3.681179838651355,
     "note": "Table I p2658: 212 cases; total red meat (both reported) | from Fig 1 p. 2660 (render"
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     "note": "Table I p2658: 100 cases; excluded from type-of-meat strata (items not specified) | f"
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     "note": "Table I p2658: 212 cases; total red meat only | from Fig 1 p. 2660 (rendered): RR (95"
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     "note": "Table I p2658: 145 cases; total red meat only | from Fig 1 p. 2660 (rendered): RR (95"
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     "label": "singh1998",
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     "note": "Table I p2658: 157 cases; fresh red meat only | from Fig 1 p. 2660 (rendered): RR (95"
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     "note": "exposure: unprocessed red meat Q4 vs Q1, multivariate"
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     "note": "Table I p2658: 102 cases; fresh red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
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     "label": "flood2003",
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     "note": "Table I p2658: 487 cases; total red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
    {
     "label": "wei2004_nhs",
     "cohort": "nhs",
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     "note": "Table I p2658: 876 cases; fresh red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
    {
     "label": "wei2004_hpfs",
     "cohort": "hpfs",
     "rr": 1.24,
     "lo": 0.78,
     "hi": 1.96,
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     "note": "Table I p2659: 602 cases; fresh red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
    {
     "label": "english2004",
     "cohort": "mccs",
     "rr": 1.4,
     "lo": 1.0,
     "hi": 1.9,
     "w": 9.726898875538058,
     "note": "Table I p2659: 451 cases; fresh red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
    {
     "label": "larsson2005",
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     "rr": 1.22,
     "lo": 0.98,
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     "note": "exposure: red meat main dish (unprocessed) ≥4 servings/week"
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     "label": "chao2005",
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     "lo": 0.93,
     "hi": 2.0,
     "w": 6.834538303820974,
     "note": "Table I p2659: 1667 cases; total red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
    {
     "label": "norat2005",
     "cohort": "epic",
     "rr": 1.17,
     "lo": 0.92,
     "hi": 1.49,
     "w": 17.23727003556295,
     "note": "exposure: fresh red meat ≥80 vs <10 g/day, model ‡"
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    "english2004": [
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  {
   "name": "CRC HvL – corrected: model",
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   "I2": 0.0,
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   "rows": [
    {
     "label": "bostick1994",
     "cohort": "iwhs",
     "rr": 1.04,
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     "hi": 1.76,
     "w": 3.437973873798877,
     "note": "Table I p2658: 212 cases; total red meat (both reported) | from Fig 1 p. 2660 (render"
    },
    {
     "label": "kato1997",
     "cohort": "nyuwhs",
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     "hi": 2.22,
     "w": 2.6734263656801334,
     "note": "Table I p2658: 100 cases; excluded from type-of-meat strata (items not specified) | f"
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    {
     "label": "chen1998",
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     "hi": 2.02,
     "w": 3.1571700949288592,
     "note": "Table I p2658: 212 cases; total red meat only | from Fig 1 p. 2660 (rendered): RR (95"
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    {
     "label": "hsing1998",
     "cohort": "hsing1998",
     "rr": 1.9,
     "lo": 0.9,
     "hi": 4.3,
     "w": 1.530038559460045,
     "note": "Table I p2658: 145 cases; total red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
    {
     "label": "singh1998",
     "cohort": "ahs",
     "rr": 1.41,
     "lo": 0.9,
     "hi": 2.21,
     "w": 4.637332252683408,
     "note": "Table I p2658: 157 cases; fresh red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
    {
     "label": "pietinen1999",
     "cohort": "atbc",
     "rr": 1.1,
     "lo": 0.7,
     "hi": 1.7,
     "w": 4.753551434715315,
     "note": "Table I p2658: 185 cases; total red meat (both reported) | from Fig 1 p. 2660 (render"
    },
    {
     "label": "jarvinen2001",
     "cohort": "fmches",
     "rr": 1.5,
     "lo": 0.77,
     "hi": 2.94,
     "w": 2.0849659802612877,
     "note": "Table I p2658: 109 cases; excluded from type-of-meat strata (items not specified) | f"
    },
    {
     "label": "tiemersma2002",
     "cohort": "monica_nl",
     "rr": 1.6,
     "lo": 0.9,
     "hi": 2.9,
     "w": 2.733617017656319,
     "note": "Table I p2658: 102 cases; fresh red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
    {
     "label": "flood2003",
     "cohort": "bcddp",
     "rr": 1.1,
     "lo": 0.83,
     "hi": 1.45,
     "w": 12.024312482956438,
     "note": "Table I p2658: 487 cases; total red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
    {
     "label": "wei2004_nhs",
     "cohort": "nhs",
     "rr": 1.21,
     "lo": 0.72,
     "hi": 2.03,
     "w": 3.4832951342263456,
     "note": "Table I p2658: 876 cases; fresh red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
    {
     "label": "wei2004_hpfs",
     "cohort": "hpfs",
     "rr": 1.24,
     "lo": 0.78,
     "hi": 1.96,
     "w": 4.408190700621562,
     "note": "Table I p2659: 602 cases; fresh red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
    {
     "label": "english2004",
     "cohort": "mccs",
     "rr": 1.4,
     "lo": 1.0,
     "hi": 1.9,
     "w": 9.084267999097532,
     "note": "Table I p2659: 451 cases; fresh red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
    {
     "label": "larsson2005",
     "cohort": "smc",
     "rr": 1.32,
     "lo": 1.03,
     "hi": 1.68,
     "w": 15.636057748934066,
     "note": "Table I p2659: 733 cases; total red meat (both reported) | from Fig 1 p. 2660 (render"
    },
    {
     "label": "chao2005",
     "cohort": "cps2",
     "rr": 1.2828350156563866,
     "lo": 1.0441240901214999,
     "hi": 1.5761207819681886,
     "w": 22.0706089315611,
     "note": "model: fixed-effect pool of colon and rectum as fn 6 states"
    },
    {
     "label": "norat2005",
     "cohort": "epic",
     "rr": 1.35,
     "lo": 0.96,
     "hi": 1.88,
     "w": 8.285191423418716,
     "note": "Table I p2659: 1329 cases; total red meat (both reported) | from Fig 1 p. 2660 (render"
    }
   ],
   "loo": {
    "bostick1994": [
     1.2867786056059445,
     1.1661494451545933,
     1.4198859217616604
    ],
    "kato1997": [
     1.2787208428953154,
     1.1592960687232208,
     1.4104481488113187
    ],
    "chen1998": [
     1.2810559087541145,
     1.1611290357741813,
     1.413369393746687
    ],
    "hsing1998": [
     1.2695373976682276,
     1.1516275802895861,
     1.3995194554761654
    ],
    "singh1998": [
     1.2712730351097057,
     1.1513867482760156,
     1.4036422880642847
    ],
    "pietinen1999": [
     1.2869608704194477,
     1.1655247413833825,
     1.4210494408080325
    ],
    "jarvinen2001": [
     1.2730314639711913,
     1.1544786468029782,
     1.4037584088267727
    ],
    "tiemersma2002": [
     1.269334953514893,
     1.150751859090852,
     1.4001378416086925
    ],
    "flood2003": [
     1.3037654855716434,
     1.1760133663588026,
     1.445395511643574
    ],
    "wei2004_nhs": [
     1.2798947484529435,
     1.1598841125592056,
     1.412322618595921
    ],
    "wei2004_hpfs": [
     1.2791448899547442,
     1.158653881734174,
     1.4121660275701946
    ],
    "english2004": [
     1.2657489824004065,
     1.143643019683121,
     1.4008921130752652
    ],
    "larsson2005": [
     1.2696492600240248,
     1.142741199159077,
     1.4106511996467814
    ],
    "chao2005": [
     1.2758566599473429,
     1.1434449726799838,
     1.423601708542878
    ],
    "norat2005": [
     1.2710300773028527,
     1.1489233892914963,
     1.4061141695485309
    ]
   }
  },
  {
   "name": "CRC HvL – corrected: all classes",
   "k": 13,
   "re": [
    1.2106853407437248,
    1.1028702573000342,
    1.3290402788448683
   ],
   "fe": [
    1.2106853407437248,
    1.1028702573000342,
    1.3290402788448683
   ],
   "I2": 0.0,
   "Q": 6.737149785977535,
   "tau2": 0.0,
   "published": null,
   "comment": "",
   "rows": [
    {
     "label": "bostick1994",
     "cohort": "iwhs",
     "rr": 1.04,
     "lo": 0.62,
     "hi": 1.76,
     "w": 3.1966036794882213,
     "note": "Table I p2658: 212 cases; total red meat (both reported) | from Fig 1 p. 2660 (render"
    },
    {
     "label": "kato1997",
     "cohort": "nyuwhs",
     "rr": 1.23,
     "lo": 0.68,
     "hi": 2.22,
     "w": 2.485732838897621,
     "note": "Table I p2658: 100 cases; excluded from type-of-meat strata (items not specified) | f"
    },
    {
     "label": "chen1998",
     "cohort": "phs",
     "rr": 1.17,
     "lo": 0.68,
     "hi": 2.02,
     "w": 2.9355143211336006,
     "note": "Table I p2658: 212 cases; total red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
    {
     "label": "singh1998",
     "cohort": "ahs",
     "rr": 1.41,
     "lo": 0.9,
     "hi": 2.21,
     "w": 4.311758578187605,
     "note": "Table I p2658: 157 cases; fresh red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
    {
     "label": "pietinen1999",
     "cohort": "atbc",
     "rr": 0.8,
     "lo": 0.5,
     "hi": 1.2,
     "w": 4.540118900550383,
     "note": "exposure: unprocessed red meat Q4 vs Q1, multivariate"
    },
    {
     "label": "tiemersma2002",
     "cohort": "monica_nl",
     "rr": 1.6,
     "lo": 0.9,
     "hi": 2.9,
     "w": 2.541697679423086,
     "note": "Table I p2658: 102 cases; fresh red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
    {
     "label": "flood2003",
     "cohort": "bcddp",
     "rr": 1.1,
     "lo": 0.83,
     "hi": 1.45,
     "w": 11.180120308437012,
     "note": "Table I p2658: 487 cases; total red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
    {
     "label": "wei2004_nhs",
     "cohort": "nhs",
     "rr": 1.21,
     "lo": 0.72,
     "hi": 2.03,
     "w": 3.238743065405486,
     "note": "Table I p2658: 876 cases; fresh red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
    {
     "label": "wei2004_hpfs",
     "cohort": "hpfs",
     "rr": 1.24,
     "lo": 0.78,
     "hi": 1.96,
     "w": 4.098704391235575,
     "note": "Table I p2659: 602 cases; fresh red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
    {
     "label": "english2004",
     "cohort": "mccs",
     "rr": 1.4,
     "lo": 1.0,
     "hi": 1.9,
     "w": 8.446487837699912,
     "note": "Table I p2659: 451 cases; fresh red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
    {
     "label": "larsson2005",
     "cohort": "smc",
     "rr": 1.22,
     "lo": 0.98,
     "hi": 1.53,
     "w": 17.53520001171785,
     "note": "exposure: red meat main dish (unprocessed) ≥4 servings/week"
    },
    {
     "label": "chao2005",
     "cohort": "cps2",
     "rr": 1.2828350156563866,
     "lo": 1.0441240901214999,
     "hi": 1.5761207819681886,
     "w": 20.521095362838423,
     "note": "model: fixed-effect pool of colon and rectum as fn 6 states"
    },
    {
     "label": "norat2005",
     "cohort": "epic",
     "rr": 1.17,
     "lo": 0.92,
     "hi": 1.49,
     "w": 14.968223024985223,
     "note": "exposure: fresh red meat ≥80 vs <10 g/day, model ‡"
    }
   ],
   "loo": {
    "bostick1994": [
     1.2167760198396578,
     1.106726767272347,
     1.3377682064253371
    ],
    "kato1997": [
     1.2101969760207798,
     1.1011238603061138,
     1.3300744571665952
    ],
    "chen1998": [
     1.211937581615076,
     1.102466579574243,
     1.3322786639919966
    ],
    "singh1998": [
     1.202399614206924,
     1.093048405805207,
     1.3226905821978854
    ],
    "pietinen1999": [
     1.234779414285389,
     1.1223555201880535,
     1.3584645636059276
    ],
    "tiemersma2002": [
     1.2019137652671323,
     1.0935575495410799,
     1.3210065622470912
    ],
    "flood2003": [
     1.22538484270507,
     1.1099203251874108,
     1.3528610825986886
    ],
    "wei2004_nhs": [
     1.2107082868295134,
     1.1011850915020611,
     1.3311245921412036
    ],
    "wei2004_hpfs": [
     1.2094480282534226,
     1.0995723257755974,
     1.3303031540142771
    ],
    "english2004": [
     1.1945659802885014,
     1.0836174018561404,
     1.3168742757529774
    ],
    "larsson2005": [
     1.2087138719396124,
     1.0907303684854646,
     1.3394595643723655
    ],
    "chao2005": [
     1.1927251379109618,
     1.0742468933924767,
     1.3242702988995079
    ],
    "norat2005": [
     1.2179922850515237,
     1.1008214670389567,
     1.3476346990538226
    ]
   }
  },
  {
   "name": "CRC HvL – corrected: errors only (model choices as published)",
   "k": 13,
   "re": [
    1.2036517253811878,
    1.0881068235407714,
    1.3314662169829
   ],
   "fe": [
    1.2036517253811878,
    1.0881068235407714,
    1.3314662169829
   ],
   "I2": 0.0,
   "Q": 6.775166394589668,
   "tau2": 0.0,
   "published": null,
   "comment": "",
   "rows": [
    {
     "label": "bostick1994",
     "cohort": "iwhs",
     "rr": 1.04,
     "lo": 0.62,
     "hi": 1.76,
     "w": 3.74249215692671,
     "note": "Table I p2658: 212 cases; total red meat (both reported) | from Fig 1 p. 2660 (render"
    },
    {
     "label": "kato1997",
     "cohort": "nyuwhs",
     "rr": 1.23,
     "lo": 0.68,
     "hi": 2.22,
     "w": 2.9102249094823365,
     "note": "Table I p2658: 100 cases; excluded from type-of-meat strata (items not specified) | f"
    },
    {
     "label": "chen1998",
     "cohort": "phs",
     "rr": 1.17,
     "lo": 0.68,
     "hi": 2.02,
     "w": 3.4368162039866714,
     "note": "Table I p2658: 212 cases; total red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
    {
     "label": "singh1998",
     "cohort": "ahs",
     "rr": 1.41,
     "lo": 0.9,
     "hi": 2.21,
     "w": 5.048083616049668,
     "note": "Table I p2658: 157 cases; fresh red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
    {
     "label": "pietinen1999",
     "cohort": "atbc",
     "rr": 0.8,
     "lo": 0.5,
     "hi": 1.2,
     "w": 5.315441349784362,
     "note": "exposure: unprocessed red meat Q4 vs Q1, multivariate"
    },
    {
     "label": "tiemersma2002",
     "cohort": "monica_nl",
     "rr": 1.6,
     "lo": 0.9,
     "hi": 2.9,
     "w": 2.975746944032375,
     "note": "Table I p2658: 102 cases; fresh red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
    {
     "label": "flood2003",
     "cohort": "bcddp",
     "rr": 1.1,
     "lo": 0.83,
     "hi": 1.45,
     "w": 13.089365077162588,
     "note": "Table I p2658: 487 cases; total red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
    {
     "label": "wei2004_nhs",
     "cohort": "nhs",
     "rr": 1.21,
     "lo": 0.72,
     "hi": 2.03,
     "w": 3.791827744664731,
     "note": "Table I p2658: 876 cases; fresh red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
    {
     "label": "wei2004_hpfs",
     "cohort": "hpfs",
     "rr": 1.24,
     "lo": 0.78,
     "hi": 1.96,
     "w": 4.798645867859368,
     "note": "Table I p2659: 602 cases; fresh red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
    {
     "label": "english2004",
     "cohort": "mccs",
     "rr": 1.4,
     "lo": 1.0,
     "hi": 1.9,
     "w": 9.88890636928432,
     "note": "Table I p2659: 451 cases; fresh red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
    {
     "label": "larsson2005",
     "cohort": "smc",
     "rr": 1.22,
     "lo": 0.98,
     "hi": 1.53,
     "w": 20.52971062227579,
     "note": "exposure: red meat main dish (unprocessed) ≥4 servings/week"
    },
    {
     "label": "chao2005",
     "cohort": "cps2",
     "rr": 1.36,
     "lo": 0.93,
     "hi": 2.0,
     "w": 6.94837175019302,
     "note": "Table I p2659: 1667 cases; total red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
    {
     "label": "norat2005",
     "cohort": "epic",
     "rr": 1.17,
     "lo": 0.92,
     "hi": 1.49,
     "w": 17.524367388298064,
     "note": "exposure: fresh red meat ≥80 vs <10 g/day, model ‡"
    }
   ],
   "loo": {
    "bostick1994": [
     1.2105102171936064,
     1.0921825496438418,
     1.3416575703466005
    ],
    "kato1997": [
     1.2028707206160256,
     1.0857694361767438,
     1.3326014919062317
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    "chen1998": [
     1.2048671112406852,
     1.087268203349166,
     1.3351855147402596
    ],
    "singh1998": [
     1.1935688095035946,
     1.0761384643972123,
     1.3238133847560283
    ],
    "pietinen1999": [
     1.2315737041484782,
     1.1102419742014586,
     1.3661650559022893
    ],
    "tiemersma2002": [
     1.1931895111495407,
     1.0769934663919258,
     1.3219218629866645
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    "flood2003": [
     1.2200870338135332,
     1.0949056780991875,
     1.3595804641950648
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    "wei2004_nhs": [
     1.2034022058430083,
     1.0857407157422863,
     1.333814646563886
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    "wei2004_hpfs": [
     1.201848054312671,
     1.0837502784872397,
     1.3328151090963345
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    "english2004": [
     1.1838558671462915,
     1.0644546669717412,
     1.316650448030686
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    "larsson2005": [
     1.1994641695691572,
     1.0710791847260257,
     1.3432380300138504
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    "chao2005": [
     1.1927251379109618,
     1.0742468933924767,
     1.3242702988995079
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    "norat2005": [
     1.2109257701017087,
     1.0835673559666095,
     1.353253411171979
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   }
  },
  {
   "name": "CRC HvL – corrected + follow-ups",
   "k": 13,
   "re": [
    1.1476976162253911,
    1.05450328314777,
    1.2491282287500107
   ],
   "fe": [
    1.1476976162253911,
    1.05450328314777,
    1.2491282287500107
   ],
   "I2": 0.0,
   "Q": 11.497227249500503,
   "tau2": 0.0,
   "published": null,
   "comment": "",
   "rows": [
    {
     "label": "bostick1994",
     "cohort": "iwhs",
     "rr": 1.04,
     "lo": 0.62,
     "hi": 1.76,
     "w": 2.635386511821576,
     "note": "Table I p2658: 212 cases; total red meat (both reported) | from Fig 1 p. 2660 (render"
    },
    {
     "label": "kato1997",
     "cohort": "nyuwhs",
     "rr": 1.23,
     "lo": 0.68,
     "hi": 2.22,
     "w": 2.0493209207190626,
     "note": "Table I p2658: 100 cases; excluded from type-of-meat strata (items not specified) | f"
    },
    {
     "label": "chen1998",
     "cohort": "phs",
     "rr": 1.17,
     "lo": 0.68,
     "hi": 2.02,
     "w": 2.42013575120865,
     "note": "Table I p2658: 212 cases; total red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
    {
     "label": "singh1998",
     "cohort": "ahs",
     "rr": 1.41,
     "lo": 0.9,
     "hi": 2.21,
     "w": 3.5547573420192777,
     "note": "Table I p2658: 157 cases; fresh red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
    {
     "label": "pietinen1999",
     "cohort": "atbc",
     "rr": 0.8,
     "lo": 0.5,
     "hi": 1.2,
     "w": 3.7430251955701572,
     "note": "exposure: unprocessed red meat Q4 vs Q1, multivariate"
    },
    {
     "label": "tiemersma2002",
     "cohort": "monica_nl",
     "rr": 1.6,
     "lo": 0.9,
     "hi": 2.9,
     "w": 2.095460198729488,
     "note": "Table I p2658: 102 cases; fresh red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
    {
     "label": "flood2003",
     "cohort": "bcddp",
     "rr": 1.1,
     "lo": 0.83,
     "hi": 1.45,
     "w": 9.217263450724232,
     "note": "Table I p2658: 487 cases; total red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
    {
     "label": "wei2004_nhs",
     "cohort": "nhs",
     "rr": 0.96,
     "lo": 0.76,
     "hi": 1.21,
     "w": 13.264512093301972,
     "note": "follow-up: NHS → Bernstein 2015 women >1 svg/d vs lowest, unprocessed red meat"
    },
    {
     "label": "wei2004_hpfs",
     "cohort": "hpfs",
     "rr": 0.98,
     "lo": 0.75,
     "hi": 1.27,
     "w": 10.341394171930409,
     "note": "follow-up: HPFS → Bernstein 2015 men >1 svg/d vs lowest, unprocessed red meat"
    },
    {
     "label": "english2004",
     "cohort": "mccs",
     "rr": 1.4,
     "lo": 1.0,
     "hi": 1.9,
     "w": 6.96356581911435,
     "note": "Table I p2659: 451 cases; fresh red meat only | from Fig 1 p. 2660 (rendered): RR (95"
    },
    {
     "label": "larsson2005",
     "cohort": "smc",
     "rr": 1.22,
     "lo": 0.98,
     "hi": 1.53,
     "w": 14.456602765461795,
     "note": "exposure: red meat main dish (unprocessed) ≥4 servings/week"
    },
    {
     "label": "chao2005",
     "cohort": "cps2",
     "rr": 1.2828350156563866,
     "lo": 1.0441240901214999,
     "hi": 1.5761207819681886,
     "w": 16.918274315346807,
     "note": "model: fixed-effect pool of colon and rectum as fn 6 states"
    },
    {
     "label": "norat2005",
     "cohort": "epic",
     "rr": 1.17,
     "lo": 0.92,
     "hi": 1.49,
     "w": 12.340301464052217,
     "note": "exposure: fresh red meat ≥80 vs <10 g/day, model ‡"
    }
   ],
   "loo": {
    "bostick1994": [
     1.1507036684216772,
     1.0539717732129024,
     1.25631346699418
    ],
    "kato1997": [
     1.1457611236130474,
     1.0492530844632784,
     1.2511457643744262
    ],
    "chen1998": [
     1.1469061427289295,
     1.0498333266214972,
     1.2529547947029485
    ],
    "singh1998": [
     1.1390235478288024,
     1.0449162574200155,
     1.2416063328479907
    ],
    "pietinen1999": [
     1.1639178682259228,
     1.0676637849144348,
     1.2688496351725052
    ],
    "tiemersma2002": [
     1.1395651871699295,
     1.0460877485657325,
     1.241395683670065
    ],
    "flood2003": [
     1.1524906798864842,
     1.051875900528747,
     1.2627295354495207
    ],
    "wei2004_nhs": [
     1.1794735458006793,
     1.0769519190521002,
     1.2917548319780896
    ],
    "wei2004_hpfs": [
     1.1687997123732954,
     1.0688021351190427,
     1.278153105010165
    ],
    "english2004": [
     1.1307538600520715,
     1.0357070623045508,
     1.234523098816801
    ],
    "larsson2005": [
     1.1359005191966158,
     1.0354581528804552,
     1.2460860788259247
    ],
    "chao2005": [
     1.1219748677146832,
     1.022426732355304,
     1.231215464098336
    ],
    "norat2005": [
     1.1443660168400702,
     1.042326304503008,
     1.2563950222121913
    ]
   }
  },
  {
   "name": "DR reconstruction per 120 g – our GL values for Larsson's DR studies where gram doses exist",
   "k": 8,
   "re": [
    1.2651729482098608,
    1.0958260183572637,
    1.4606904399674325
   ],
   "fe": [
    1.2651729482098608,
    1.0958260183572637,
    1.4606904399674325
   ],
   "I2": 0.0,
   "Q": 4.01006689739562,
   "tau2": 0.0,
   "published": [
    1.28,
    1.18,
    1.39
   ],
   "comment": "not reproducible from the paper; studies without gram-based categories in our table: chen1998, hsing1998, flood2003, wei2004, chao2005",
   "rows": [
    {
     "label": "bostick1994",
     "cohort": "iwhs",
     "rr": 0.9250029663381212,
     "lo": 0.36392328672698904,
     "hi": 2.351536840046294,
     "w": 2.372509263273523,
     "note": "database GL/continuous per 100 g → per 120 g (colon, red_main_dish)"
    },
    {
     "label": "singh1998",
     "cohort": "ahs",
     "rr": 2.9868192194663825,
     "lo": 0.3964004004001619,
     "hi": 22.506497628115092,
     "w": 0.5062899362131162,
     "note": "database GL/continuous per 100 g → per 120 g (colon, red_undefined)"
    },
    {
     "label": "pietinen1999",
     "cohort": "atbc",
     "rr": 0.8040337313703267,
     "lo": 0.36453174099925506,
     "hi": 1.773395958321603,
     "w": 3.3002141212742337,
     "note": "database GL/continuous per 100 g → per 120 g (colorectal, red_unprocessed)"
    },
    {
     "label": "jarvinen2001",
     "cohort": "fmches",
     "rr": 1.4702850106490482,
     "lo": 0.9030150588902051,
     "hi": 2.3939443975216146,
     "w": 8.689678942588849,
     "note": "database GL/continuous per 100 g → per 120 g (colorectal, red_undefined)"
    },
    {
     "label": "tiemersma2002",
     "cohort": "monica_nl",
     "rr": 2.186337110723703,
     "lo": 0.8293253316840454,
     "hi": 5.764099491597568,
     "w": 2.1974227909922663,
     "note": "database GL/continuous per 100 g → per 120 g (colorectal, red_unprocessed)"
    },
    {
     "label": "english2004",
     "cohort": "mccs",
     "rr": 1.2298933623228532,
     "lo": 0.8680902033699593,
     "hi": 1.7137589924928207,
     "w": 17.85533468545099,
     "note": "database GL/continuous per 100 g → per 120 g (colorectal, red_unprocessed)"
    },
    {
     "label": "larsson2005",
     "cohort": "smc",
     "rr": 1.2759932758156731,
     "lo": 0.8786492067376667,
     "hi": 1.8531675900826612,
     "w": 14.83162376949722,
     "note": "database GL/continuous per 100 g → per 120 g (colorectal, red_main_dish)"
    },
    {
     "label": "norat2005",
     "cohort": "epic",
     "rr": 1.2570207430874425,
     "lo": 1.0240477462785176,
     "hi": 1.5360425453326891,
     "w": 50.2469264907098,
     "note": "database GL/continuous per 100 g → per 120 g (colorectal, red_unprocessed)"
    }
   ],
   "loo": {
    "bostick1994": [
     1.2748382529390987,
     1.1022828148165886,
     1.4744061590284672
    ],
    "singh1998": [
     1.2596547412680916,
     1.0906481077797012,
     1.454850612109332
    ],
    "pietinen1999": [
     1.2848989019698853,
     1.1102087699624543,
     1.487076334606193
    ],
    "jarvinen2001": [
     1.2472115705572946,
     1.0730741450885994,
     1.44960784755797
    ],
    "tiemersma2002": [
     1.2497186476668365,
     1.080704007813127,
     1.4451660094114216
    ],
    "english2004": [
     1.2729743819248596,
     1.0863304428557017,
     1.4916858748588215
    ],
    "larsson2005": [
     1.2632980478600815,
     1.0811388561805066,
     1.4761489225955984
    ],
    "norat2005": [
     1.2734597335209192,
     1.038742313715104,
     1.561214626079009
    ]
   },
   "reproduced": false
  }
 ],
 "deviations": [
  {
   "study": "hsing1998",
   "class": "inclusion",
   "text": "Lutheran Brotherhood: fatal cases only (mortality); Larsson's own sensitivity analysis excluding mortality studies gives 1.27 (1.14–1.42)",
   "page": "Table I fn7; text p2660",
   "alternative": "remove",
   "alt_note": "mortality study",
   "outcome": "colorectal"
  },
  {
   "study": "pietinen1999",
   "class": "exposure",
   "text": "Larsson's row 203 vs 79 g/day is ATBC's red meat *including* processed (Chan 2011 S1; Pietinen Table 5); the unprocessed row (99 vs 35 g/day) gives 0.8 (0.5–1.2)",
   "page": "Pietinen 1999 Table 5",
   "alternative": [
    0.8,
    0.5,
    1.2
   ],
   "alt_note": "unprocessed red meat Q4 vs Q1, multivariate",
   "outcome": "colorectal"
  },
  {
   "study": "norat2005",
   "class": "exposure",
   "text": "Larsson chose EPIC's total red meat (fresh + processed, ≥160 vs <20 g) 1.35 (0.96–1.88); the fresh red meat row (≥80 vs <10 g) is 1.17 (0.92–1.49) — as WCRF 2007 Fig 4.3.1 uses",
   "page": "Norat 2005 Table 3; Larsson Table I fn 4 (stated rule: total red meat preferred)",
   "alternative": [
    1.17,
    0.92,
    1.49
   ],
   "alt_note": "fresh red meat ≥80 vs <10 g/day, model ‡",
   "outcome": "colorectal"
  },
  {
   "study": "larsson2005",
   "class": "exposure",
   "text": "SMC total red meat (incl. processed) ≥94 g vs <47 g 1.32 (1.03–1.68); the paper's unprocessed 'red meat as main dish' top category gives 1.22 (0.98–1.53)",
   "page": "Larsson 2005 Table II",
   "alternative": [
    1.22,
    0.98,
    1.53
   ],
   "alt_note": "red meat main dish (unprocessed) ≥4 servings/week",
   "outcome": "colorectal"
  },
  {
   "study": "chao2005",
   "class": "exposure",
   "text": "CPS-II Nutrition Cohort 'red meat' includes processed meat (beef, pork, lamb and processed); no unprocessed row exists",
   "page": "Chao 2005 Methods",
   "alternative": null,
   "alt_note": "",
   "outcome": "colorectal"
  },
  {
   "study": "chao2005",
   "class": "model",
   "text": "Larsson's CRC row for Chao, 1.36 (0.93–2.00), is a random-effects pool of Chao's colon 1.15 (0.90–1.46) and rectum 1.71 (1.15–2.52); footnote 6 says inverse-variance weighting, which as a fixed-effect pool gives 1.28 (1.04–1.58)",
   "page": "Larsson Table I fn 6; Chao 2005 Table 2",
   "alternative": [
    1.2828350156563866,
    1.0441240901214999,
    1.5761207819681886
   ],
   "alt_note": "fixed-effect pool of colon and rectum as fn 6 states",
   "outcome": "colorectal"
  },
  {
   "study": "bostick1994",
   "class": "exposure",
   "text": "Table II fn 4 lists Bostick as reporting both total and fresh red meat; Larsson's row 1.04 (0.62–1.76) is the paper's 'red meat' (>11 vs <4 servings/week) and the main-dish variable includes ham — neither is a clean unprocessed row",
   "page": "Larsson Table II fn 4; Bostick 1994 Table 3",
   "alternative": null,
   "alt_note": "",
   "outcome": "colorectal"
  },
  {
   "study": "flood2003",
   "class": "exposure",
   "text": "BCDDP 'red meat' includes processed meat; no unprocessed row",
   "page": "Flood 2003 Methods",
   "alternative": null,
   "alt_note": "",
   "outcome": "colorectal"
  },
  {
   "study": "singh1998",
   "class": "cases",
   "text": "157 colon cases include 22 rectosigmoid cases",
   "page": "Singh 1998 Methods",
   "alternative": null,
   "alt_note": "",
   "outcome": "colorectal"
  },
  {
   "study": "chen1998",
   "class": "inclusion",
   "text": "Physicians' Health Study nested case-control (212 cases); Larsson's sensitivity excluding nested case-control studies gives 1.28 (1.15–1.42)",
   "page": "Table I; text p2660",
   "alternative": null,
   "alt_note": "",
   "outcome": "colorectal"
  },
  {
   "study": "wei2004_nhs",
   "class": "exposure",
   "text": "'red meat as main dish' excludes hamburger and mixed dishes (both NHS and HPFS)",
   "page": "Wei 2004 Table II",
   "alternative": null,
   "alt_note": "",
   "outcome": "colorectal"
  },
  {
   "study": "jarvinen2001",
   "class": "exposure",
   "text": "Järvinen's 'red meat' row is near-total meat (quartile cut-points 91–94 % of those for 'Meat, all'); Larsson's own Table II fn 4 excludes it from the type-of-meat strata (items not specified). Same deviation as in CUP 2010/2016 (correction R106)",
   "page": "Järvinen 2001 Tables 2–3; Larsson Table II fn 4",
   "alternative": "remove",
   "alt_note": "no red-meat row in the paper",
   "outcome": "colorectal"
  }
 ],
 "notes": [
  "Per-study per-120 g estimates (Table III, 1.28 (1.18–1.39), 14 studies) are not printed anywhere in the paper; the dose-response analysis cannot be reproduced from printed values (protocol R3). Our own GL per-100 g reconstruction for the same 14 studies is reported under 'DR reconstruction'."
 ]
}