{
 "id": "norat2002",
 "title": "Norat et al. 2002 (Int J Cancer 98:241): red meat, cohort studies, highest vs lowest (Table I: 1.27 (1.11–1.45), n = 9) and per 120 g/day (Table II: 1.22 (1.05–1.41), n = 9)",
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     "note": "paper: red_total Q5 >=134 vs lowest (colon, Age-adjusted, energy-adjusted )"
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    {
     "label": "pietinen1999",
     "cohort": "atbc",
     "rr": 0.8,
     "lo": 0.5,
     "hi": 1.2,
     "w": 16.218035683457945,
     "note": "exposure: unprocessed red meat Q4 vs Q1"
    }
   ],
   "loo": {
    "willett1990": [
     1.2081726654908023,
     0.9555996219171021,
     1.5275028957323897
    ],
    "chen1998": [
     1.2878137156289151,
     0.9939088243778715,
     1.6686280728013991
    ],
    "giovannucci1994": [
     1.1929003962938562,
     0.944781477183598,
     1.5061804129776644
    ],
    "bostick1994": [
     1.3123856264754759,
     1.0199793254516296,
     1.688618572554691
    ],
    "kato1997": [
     1.277979164250921,
     0.9879446500489678,
     1.6531601686172714
    ],
    "singh1998": [
     1.2485598054002995,
     0.956780346841932,
     1.62932024346731
    ],
    "pietinen1999": [
     1.412332554165668,
     1.1581838401973614,
     1.722250971155161
    ]
   }
  },
  {
   "name": "HvL – corrected + follow-ups",
   "k": 7,
   "re": [
    1.0143970407292424,
    0.8841997190989146,
    1.1637657579091933
   ],
   "fe": [
    1.0143970407292424,
    0.8841997190989146,
    1.1637657579091933
   ],
   "I2": 0.0,
   "Q": 4.157023585077593,
   "tau2": 0.0,
   "published": null,
   "comment": "",
   "rows": [
    {
     "label": "willett1990",
     "cohort": "nhs",
     "rr": 0.96,
     "lo": 0.76,
     "hi": 1.21,
     "w": 34.898775090783545,
     "note": "follow-up: NHS → Bernstein 2015 women >1 svg/d vs lowest, unprocessed red meat"
    },
    {
     "label": "chen1998",
     "cohort": "phs",
     "rr": 1.17,
     "lo": 0.68,
     "hi": 2.02,
     "w": 6.367348657569082,
     "note": "Appendix III: >1 vs <=0.5 servings/day (red meat)"
    },
    {
     "label": "giovannucci1994",
     "cohort": "hpfs",
     "rr": 0.98,
     "lo": 0.75,
     "hi": 1.27,
     "w": 27.208086267536334,
     "note": "follow-up: HPFS → Bernstein 2015 men >1 svg/d vs lowest, unprocessed red meat"
    },
    {
     "label": "bostick1994",
     "cohort": "iwhs",
     "rr": 1.04,
     "lo": 0.62,
     "hi": 1.76,
     "w": 6.933670873562524,
     "note": "Appendix III: >11 vs <4 servings/week (red meat)"
    },
    {
     "label": "kato1997",
     "cohort": "nyuwhs",
     "rr": 1.23,
     "lo": 0.68,
     "hi": 2.22,
     "w": 5.391739205931747,
     "note": "Appendix III: Q4 vs Q1 (red meat)"
    },
    {
     "label": "singh1998",
     "cohort": "ahs",
     "rr": 1.41,
     "lo": 0.9,
     "hi": 2.21,
     "w": 9.352524699652221,
     "note": "Appendix III: >=1 time/week vs never (red meat)"
    },
    {
     "label": "pietinen1999",
     "cohort": "atbc",
     "rr": 0.8,
     "lo": 0.5,
     "hi": 1.2,
     "w": 9.847855204964548,
     "note": "exposure: unprocessed red meat Q4 vs Q1"
    }
   ],
   "loo": {
    "willett1990": [
     1.0448157913670484,
     0.8812540603360841,
     1.2387347610899317
    ],
    "chen1998": [
     1.004600198961602,
     0.8716468328240835,
     1.1578331059654896
    ],
    "giovannucci1994": [
     1.0275616605444822,
     0.8747505447027161,
     1.2070675149791135
    ],
    "bostick1994": [
     1.0125149797861464,
     0.8781353400514051,
     1.1674585198123641
    ],
    "kato1997": [
     1.003316745950156,
     0.8711723152236475,
     1.1555056044745684
    ],
    "singh1998": [
     0.9805118447266762,
     0.8487762122768593,
     1.1326937109492328
    ],
    "pietinen1999": [
     1.0410513815607718,
     0.9008253886960113,
     1.2031054993004004
    ]
   }
  }
 ],
 "deviations": [
  {
   "study": "pietinen1999",
   "class": "exposure",
   "text": "Norat's ATBC row (203 vs 79 g/day) is red meat including processed (Pietinen Table 5); the paper's red meat (beef, pork, lamb) row 99 vs 35 g/day gives 0.8 (0.5–1.2)",
   "page": "Pietinen 1999 Table 5; Chan 2011 S1",
   "alternative": [
    0.8,
    0.5,
    1.2
   ],
   "alt_note": "unprocessed red meat Q4 vs Q1",
   "outcome": "colon/colorectal"
  },
  {
   "study": "hsing1998",
   "class": "inclusion",
   "text": "fatal colorectal cancer only (Lutheran Brotherhood mortality cohort)",
   "page": "Hsing 1998",
   "alternative": "remove",
   "alt_note": "mortality",
   "outcome": "colon/colorectal"
  },
  {
   "study": "chen1998",
   "class": "inclusion",
   "text": "nested case-control (Physicians' Health Study)",
   "page": "Chen 1998",
   "alternative": null,
   "alt_note": "",
   "outcome": "colon/colorectal"
  },
  {
   "study": "giovannucci1994",
   "class": "exposure",
   "text": "HPFS 'red meat' here is total red meat including processed (Giovannucci Table 2, beef/pork/lamb + processed)",
   "page": "Giovannucci 1994 Table 2",
   "alternative": null,
   "alt_note": "",
   "outcome": "colon/colorectal"
  },
  {
   "study": "willett1990",
   "class": "exposure",
   "text": "NHS 'red meat' quintiles (g/day) include processed meat",
   "page": "Willett 1990 Table 4 p1668",
   "alternative": null,
   "alt_note": "",
   "outcome": "colon/colorectal"
  },
  {
   "study": "thun1992",
   "class": "inclusion",
   "text": "CPS-II mortality cohort (fatal colon cancer); value read off Fig 2, not printed",
   "page": "Thun 1992; Norat Fig 2",
   "alternative": "remove",
   "alt_note": "mortality; figure-read",
   "outcome": "colon/colorectal"
  },
  {
   "study": "thun1992",
   "class": "transcription",
   "text": "Thun 1992 prints quintile-5 'fatty meats' RRs of 1.21 (men) and 1.05 (women) with NO confidence intervals (Table 4, unadjusted, conditional logistic); the single entry plotted in Norat's Fig 2 (≈1.14, 0.91–1.38) with a CI is therefore Norat's own construction, from inputs the paper does not print",
   "page": "Thun 1992 Table 4 p1495; Norat Appendix III p255; Fig 2 p245",
   "alternative": null,
   "alt_note": "",
   "outcome": "colon/colorectal"
  }
 ],
 "notes": [
  "Per-study values behind Fig 2 (HvL) and Fig 4 (per 120 g) are not printed; the cohort HvL stratum reproduces only with one value read off the figure (R3 not met strictly). Missing from the printed pool: thun1992."
 ]
}